Soil dermis

Collagenase production by human dermis in vitro.

Isolated human dermis has been shown to produce a specific collagenase in vitro. Enzyme activity becomes detectable after two days of culture, reaches a peak on the fourth day, and then begins to decline. Like collagenase obtained from cultures of whole human skin, dermal collagenase is inhibited by human serum and EDTA. The possible sources of this enzyme are discussed. Collagenolytic activity...

Abdominal wall repair using human acellular dermis.

BACKGROUND The surgical repair of abdominal wall defects that cannot be closed primarily in contaminated fields is a difficult problem. The use of nonabsorbable synthetic materials usually is contraindicated in this setting because of the risk for colonization and chronic infection of the mesh. In this study we sought to determine the safety and efficacy of implanted human acellular dermal graf...

Plasma cell leukaemia relapsing in the dermis.

The Superficial Dermis May Initiate Keloid Formation: Histological Analysis of the Keloid Dermis at Different Depths

Several studies have reported on certain aspects of the characteristics of different sites within a keloid lesion, but detailed studies on the keloid dermis at different depths within a keloid lesion are scarce. The aim of this study was to investigate the histology of the keloid dermis at different depths. This study included 19 keloid tissue samples that were collected from 19 patients and 19...

A Special Fibril of the Dermis

A new type of extracellular fibril is described in the dermis of Bufo marinus, Rana pipiens, and Amblystoma punctatum. It is restricted in distribution to the dermal micropapillae and the region immediately below them in the stratum spongiosum. The fibrils (diameter = 200 to 750 A) are lateral aggregates of fine filaments and have a unique banding pattern characterized by absence of recognizabl...